Multidrug-resistant Tuberculosis Patients in Bhutan, August 2011 to July 2012

This was posted on Monday, September 19th, 2016 By in Publication

This study aimed to describe the factors associated with multidrug-resistant tuberculosis (MDR-TB) in Bhutan. The study covered all MDR-TB patients admitted to Gidhakom Hospital, Thimphu from August 2011 to July 2012. Data were collected from MDR-TB registers, laboratory registers and inpatient records as well as from interview with patients about demographic characteristics, history of previous anti-TB treatment, compliance and contact history. There were total 19 MDR-TB patients. Majority of the patients were males (63%). Median age was 25 years for males and 30 years for females. Of the 19 cases, 47% and 37% had contacted with TB case and MDR-TB case in the same house respectively. About 74% reported previous history of anti-TB treatment. Among those with previous treatment, 79% did not comply with the directly observed treatment short-course (DOTS). It was found that 20% of new cases and 50% of previously treated persons were resistant to four first-line drugs. In conclusion, previous anti-TB treatment, non-compliance to DOTS and contact with MDR-TB were observed in majority of the cases. We highlighted the importance of early detection of MDR-TB, providing health education on prevention of disease transmission and strengthening DOTS policy. Investigation on household contacts should be given priority to identify and control the spread of TB.
Keywords: tuberculosis, multidrug-resistant, directly observed treatment short-course, Bhutan