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Dominance of Emerging G9 and G12 Genotypes and Polymorphism of VP7 and VP4 of Rotaviruses from Bhutanese Children with Severe Diarrhea Prior to the Introduction of Vaccine

Bhutan is a small landlocked country located between India and China. Part of the population is concentrated in the capital Thimphu, but most are scattered sparsely throughout the country. Diarrhea is a major cause of illness and death in Bhutanese children, and the morbidity rate from diarrhea in ,5 years old children is 314.6/1,000 population [1,2], while 13% of deaths are attributable to diarrhea [3]. Approximately 83% of the population have access to safe drinking water and 91% have access to sanitary toilets [1]. A shift from bacterial to possibly viral diarrhea has been observed, although information regarding childhood diarrhea is..